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Graphical Search for Two-Stage Designs for Phase II Clinical Trials

โœ Scribed by Sin-Ho Jung; Mark Carey; Kyung Mann Kim


Book ID
114186851
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
87 KB
Volume
22
Category
Article
ISSN
0197-2456

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Optimal three-stage designs for phase II
โœ T. Timothy Chen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 136 KB ๐Ÿ‘ 2 views

The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at