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Two-stage designs for phase II cancer trials with ordinal responses

โœ Scribed by Nigel Stallard; Louise Cockey


Book ID
116350757
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
386 KB
Volume
29
Category
Article
ISSN
1551-7144

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Optimal three-stage designs for phase II
โœ T. Timothy Chen ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 136 KB ๐Ÿ‘ 2 views

The objective of a phase II cancer clinical trial is to screen a treatment that can produce a similar or better response rate compared to the current treatment results. This screening is usually carried out in two stages as proposed by Simon. For ineffective treatment, the trial should terminate at