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Tritium labelling of benzamide drugs

✍ Scribed by Ilan Pri-Bar; Ouri Buchman

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 267 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580201004

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✦ Synopsis

Methods f o r t r i t i a t i o n o f s u l p i r i d e , s u l t o p r i d e and metoclopramide were H-metoclopramide (18.0 Ci/mmol) were obtained by hydrodebromination o f the developed and optimized. 3 H -s u l p i r i d e (7.1 Ci/mmol), 3H-sultopride (2.1 Ci/mmol) and r e l a t e d bromo d e r i v a t i v e s . The bromo d e r i v a t i v e s were prepared, i n turn, by appropriate 3 procedures s p e c i f i e d f o r each case.

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