𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Preparation of tritium labelled benzamide dopamine-D2 lignads at high specific activity

✍ Scribed by Lars Gawell; Häkan Hall; Christer Köhler

Publisher
John Wiley and Sons
Year
1985
Tongue
French
Weight
360 KB
Volume
22
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

Dz binding properties, i s described. The pyrrolidine moiety of the molecule i s labelled with tritium by hydrogenation, to a specific a c t i v i t y o f up to 58 Ci/mnol and subsequently reacted with an acid chloride. The specificity o f the label i s confirmed by 'H-"R.

📜 SIMILAR VOLUMES

Preparation of tritium labeled diphenylh
Preparation of tritium labeled diphenylhydantoin of high specific activity
✍ J. A. Kepler 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 French ⚖ 107 KB

Since its introduction to medicine several years ago, diphenylhydantoin (DPH) has been widely used in the treatment of epilespy, both in adults and children.( 2) The effects of the drug is well correlated with the plasma levels. high levels have adverse effects. ( 3 )

The synthesis of betaxolol labelled with
The synthesis of betaxolol labelled with tritium at high specific activity
✍ John Allen; André Tizot 📂 Article 📅 1988 🏛 John Wiley and Sons 🌐 French ⚖ 204 KB

## Department of Chemistry Labelled Compounds and Metabolite Synthesis Group 31, avenue Paul Vaillant-Couturier 92220 BAGNEUX (FRANCE) SmOuRY The synthesis of betaxolol, a new 8-blocking agent. labelled with tritium in high specific activity ('19 Ci/mmol) is described. The tritium was incorporated

The preparation and stability of DL-α-to
The preparation and stability of DL-α-tocopherol labelled with tritium at high specific activity
✍ E. A. Evans; R. F. Phillips 📂 Article 📅 1969 🏛 John Wiley and Sons 🌐 French ⚖ 389 KB

Hydrogen-tritium exchange labelling methods proved to be unsatisfactory for the preparation of tritiated DL-a-tocopherol at high specific activity. The preparation of a-tocopherol specijcally labelled in the 5-methyl hydrogen positions is described : the method permits specific activities in the cur

High specific activity tritium labeling
High specific activity tritium labeling of vitamin D derivative RO275646
✍ Steve A. de Keczer; Tim S. Lane; Tatyana Voronin; Mohammad R. Masjedizadeh 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 120 KB

The octahydroindenone intermediate was tritium labeled using T 2 O isotope exchange labeling, and then elaborated to the vitamin D derivative RO275646. Though this method of labeling was expected to give the minor isomer, it was the shortest and most convenient route to the high specific activity me