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“Traceless” solid-phase synthesis of furans via 1,3-dipolar cycloaddition reactions of isomünchnones

✍ Scribed by Madhusudhan R. Gowravaram; Mark A. Gallop

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
268 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

The generation and cycloaddition reactions of polymer-supported mesoionic isomtinchnones derived from a-diazocarbonyl intermediates is described in this report. This chemistry provides a method for preparing combinatorial libraries of functionalized furans and features cycloreversion as a new synthetic strategy for "traceless" synthesis of small organic molecules.

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