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Stereoselective synthesis of highly functionalised pyrrolidines via 1,3-dipolar cycloaddition reactions on a solid support
β Scribed by Sean P. Hollinshead
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 261 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The generation and cycloaddition reactions of polymer-supported mesoionic isomtinchnones derived from a-diazocarbonyl intermediates is described in this report. This chemistry provides a method for preparing combinatorial libraries of functionalized furans and features cycloreversion as a new synthe
1,3-Dipolar cycloaddition of D-glucose-derived azomethine ylides for the synthesis of chiral pyrrolidines accompanied an unexpected 1,2-elimination in the furanose moiety of the products. The C3 0 alkoxy/ hydroxy group of the furanose moiety was invariably eliminated under the reaction conditions. A