Stereoselective synthesis of isoxazole and pyrazole annulated sultams via intramolecular 1,3-dipolar cycloaddition reactions
✍ Scribed by Ugo Chiacchio; Antonino Corsaro; Giuseppe Gumina; Venerando Pistarà; Antonio Rescifina; Manlio Alessi; Anna Piperno; Giovanni Romeo; Roberto Romeo
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- French
- Weight
- 705 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
N,N'-Diarylbisnitrile imides 2 add regioselectively to ¢t-(benzothiazol-2-yl)cinnamonitriles 3 and ct-(l-methylbenzimidazol-2-yl)cinnamonitriles 7 to yield exclusively the cycloadducts 5,5'-dicyano-4,4',5,5'-tetrahydro[3,3'-bi-lH-pyrazoles] 4 and 8, respectively. Compounds 4 and 8 undergo aromatizat
## Abstract magnified image A series of isoxazolidine derivates (isomeric 2,3,5‐trisubstitutedperhydropyrrolo[3,4‐d]isoxazole‐4,6‐diones) used as anti‐inflammatory, immunosuppressive, antibacterial agent, and inhibitor for some enzymes were synthesized. These compounds were prepared by 1,3‐dipolar
## Abstract 3‐Aryl‐5‐(benzotriazol‐1‐ylmethyl)‐ 10a‐f and 3‐__p__‐methoxyphenyl‐5‐(α‐benzotriazol‐1‐yl‐α‐ethoxymethyl)‐isoxazole (13) were prepared in high yields by 1,3‐dipolar cycloadditions of 1‐propargyl‐benzotriazole (5) and (α‐ethoxypropargyl)benzotriazole (8), respectively, with nitrite oxid