Stereoselective Synthesis of Highly Substituted Δ1-Pyrrolines: exo-Selective 1,3-Dipolar Cycloaddition Reactions with Azlactones.
✍ Scribed by Satyamaheshwar Peddibhotla; Jetze J. Tepe
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 33 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract magnified image Asymmetric 1,3‐dipolar cycloadditions of chiral nitrones to 1‐propene‐1,3‐sultone (**1**) were investigated. Chiral nitrones **6a‐e** reacted with sultone **1** in toluene at 90 °C for 24‐36 h to give the corresponding isoxazolidines in moderate yields with high regiose
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