The generation and cycloaddition reactions of polymer-supported mesoionic isomtinchnones derived from a-diazocarbonyl intermediates is described in this report. This chemistry provides a method for preparing combinatorial libraries of functionalized furans and features cycloreversion as a new synthe
Solid-phase synthesis of functionalized tropane derivatives via 1,3-dipolar cycloaddition
✍ Scribed by Sandrine Caix-Haumesser; Issam Hanna; Jean-Yves Lallemand; Jean-François Peyronel
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 99 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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## Abstract magnified image A simple diastereoselective route to nicotine derivatives is presented. The one‐pot three component 1,3‐dipolar cycloaddition reaction of the Knöevenagel adducts of a number of aromatic aldehydes and malononitrile with an azomethine ylide derived __in situ__ from pyridin