𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Traceless, Self-Cleaving Solid- and Solution-Phase Parallel Synthesis of 3,4,7-Trisubstituted 3,4-Dihydroquinoxalin-2-ones

✍ Scribed by Laborde, Edgardo; Peterson, Brian T.; Robinson, Louise

Book ID
127382901
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
62 KB
Volume
3
Category
Article
ISSN
1520-4766

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Solid phase synthesis of 2,4,5-trisubsti
Solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones
✍ Adel Nefzi; Marc Giulianotti; Richard A. Houghten πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 170 KB

The solid phase synthesis of 2,4,5-trisubstituted thiomorpholin-3-ones is described. Starting from a resin-bound protected cysteine, and employing reductive alkylation and amide formation, thiomoq~holin-3one derivatives have been synthesized through intramolecular thioether formation in good yield a

Traceless synthesis of 3H-quinazolin-4-o
Traceless synthesis of 3H-quinazolin-4-ones via a combination of solid-phase and solution methodologies
✍ Donogh J.R. O'Mahony; Viktor KrchňÑk πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 French βš– 119 KB

A solid-phase traceless synthesis of quinazolin-4-ones is described. An aldehyde functionalized resin was reductively aminated with primary amines, and the resin-bound secondary amine acylated with o-nitro-benzoic acids. The nitro group was reduced with tin(II) chloride, and the aniline acylated wit