The synthesis of (\*)-colchicine 1. labelled with carbon-14 at the 7position of the B ring was achieved by a sixteen step sequence with an overall radiochemical yield of 2.5% from [Ba14C03] (Specific activity : 55 m(li-mmol-1).
Total synthesis of 7-14C (±) colchicine
✍ Scribed by R. Pontikis; Nguyen-Hoang; H. Hoellinger
- Publisher
- Elsevier Science
- Year
- 1988
- Weight
- 34 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0883-2889
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