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Total synthesis of [7-14C]-(±)-colchicine

✍ Scribed by Renée Pontikis; Nguyen Hoang Nam; Henri Hoellinger

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
479 KB
Volume
27
Category
Article
ISSN
0022-2135

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✦ Synopsis

The synthesis of (*)-colchicine 1. labelled with carbon-14 at the 7position of the B ring was achieved by a sixteen step sequence with an overall radiochemical yield of 2.5% from [Ba14C03] (Specific activity : 55 m(li-mmol-1).

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