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The synthesis of nitrogen-containing prostacyclin analogs

✍ Scribed by G.L. Bundy; J.M. Baldwin

Publisher: Elsevier Science
Year: 1978
Tongue: French
Weight: 372 KB
Volume: 19
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)94548-4

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✦ Synopsis

Structural assignments for the various synthetic intermediates were confirmed by infrared, proton magnetic resonance and mass spectroscopy on chromatographically homogeneous samples.

This cycloaddition probably involves the intermediacy of a triazoline rather than a nitrene.

See A.L. Logothetis, J. Am. Chem. Sot. _ 87 (4), 749 (1965) for a thorough study of the decomposition of olefinic asides.

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