✦ LIBER ✦

The synthesis of 1 (tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) via direct fluorination

✍ Scribed by Robert A. Earl; Leroy B. Townsend

Book ID: 112122788
Publisher: Journal of Heterocyclic Chemistry
Year: 1972
Tongue: English
Weight: 271 KB
Volume: 9
Category: Article
ISSN: 0022-152X
DOI: 10.1002/jhet.5570090533

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stereoselective metabolism of ftorafur (

Stereoselective metabolism of ftorafur (R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil)

✍ J. Lai-Sim Au; W. Sadée 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 476 KB

Metabolic activation of ftorafur [R,S-1-

Metabolic activation of ftorafur [R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil]: the microsomal oxidative pathway

✍ Yousry M. El Sayed; Wolfgang Sadée 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 354 KB

1-(tetrahydro-2-furanyl)-5-fluorouracil

1-(tetrahydro-2-furanyl)-5-fluorouracil (Ftorafur) determined in rat hair as an index of drug exposure

✍ Toshihiko Uematsu; Norio Miyazawa; Kouichirou Wada 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 361 KB

Loss of tRNA 5-methyluridine methyltrans

Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli

✍ David A. Frendewey; Dawn M. Kladianos; Virginia G. Moore; Ivan I. Kaiser 📂 Article 📅 1982 🏛 Elsevier Science 🌐 English ⚖ 783 KB

Hepatic conversion of 1-(tetrahydro-2-fu

Hepatic conversion of 1-(tetrahydro-2-furanyl)-5-fluorouracil into 5-fluorouracil in patients with hepatocellular carcinoma

✍ Kawata, Sumio ;Noda, Shuzo ;Imai, Yasuharu ;Tamura, Shinji ;Saitoh, Ryuzo ;Miyos 📂 Article 📅 1987 🏛 Springer-Verlag 🌐 English ⚖ 487 KB

High-pressure liquid chromatographic det

High-pressure liquid chromatographic determination of ftorafur [1-(tetrahydro-2-furanyl)-5-fluorouracil] and GLC-mass spectrometric determination of 5-fluorouracil and uracil in biological materials after oral administration of uracil plus ftorafur

✍ Teruyoshi Marunaka; Yukihiko Umeno; Kozo Yoshida; Masahiro Nagamachi; Yoshinori 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 591 KB

Oral adminstration of uracil plus ftorafur [ 1-(tetrahydro-2-furanyl)-5-fluorouracil] has a greater antitumor effect than that of ftorafur alone. A high-pressure liquid chromatographic method was developed for the determination of ftorafur in plasma and visceral tissues with a sensitivity of 0.025 l