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Stereoselective metabolism of ftorafur (R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil)

✍ Scribed by J. Lai-Sim Au; W. Sadée


Book ID
104687861
Publisher
Springer
Year
1981
Tongue
English
Weight
476 KB
Volume
7
Category
Article
ISSN
0344-5704

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High-pressure liquid chromatographic det
✍ Teruyoshi Marunaka; Yukihiko Umeno; Kozo Yoshida; Masahiro Nagamachi; Yoshinori 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 591 KB

Oral adminstration of uracil plus ftorafur [ 1-(tetrahydro-2-furanyl)-5-fluorouracil] has a greater antitumor effect than that of ftorafur alone. A high-pressure liquid chromatographic method was developed for the determination of ftorafur in plasma and visceral tissues with a sensitivity of 0.025 l