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Loss of tRNA 5-methyluridine methyltransferase and pseudouridine synthetase activities in 5-fluorouracil and 1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur)-treated Escherichia coli

โœ Scribed by David A. Frendewey; Dawn M. Kladianos; Virginia G. Moore; Ivan I. Kaiser


Book ID
119118950
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
783 KB
Volume
697
Category
Article
ISSN
0167-4781

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High-pressure liquid chromatographic det
โœ Teruyoshi Marunaka; Yukihiko Umeno; Kozo Yoshida; Masahiro Nagamachi; Yoshinori ๐Ÿ“‚ Article ๐Ÿ“… 1980 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 591 KB

Oral adminstration of uracil plus ftorafur [ 1-(tetrahydro-2-furanyl)-5-fluorouracil] has a greater antitumor effect than that of ftorafur alone. A high-pressure liquid chromatographic method was developed for the determination of ftorafur in plasma and visceral tissues with a sensitivity of 0.025 l