The Stereospecificity of Brefeldin A Cyclization
โ Scribed by Dipl.-Chem. Peter Raddatz; Prof. Dr. Ekkehard Winterfeldt
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 229 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Enantioconvergent Formal Synthesis of Brefeldin A via Sakai-Catalyzed Cyclization. -A formal total synthesis of the antitumor agent brefeldin A (XII) is presented by asymmetric synthesis of intermediate (XI). Key steps are the asymmetric Sakai cyclization of racemic pentenal (I) and the reductive a
A Formal Synthesis of (+)-Brefeldin A. -An advanced synthetic intermediate for (+)-brefeldin A (IX) is efficiently synthesized from Weinreb amide (I). The procedure involves the highly stereoselective construction of the hydroxycyclopentane moiety via an oxabicycloheptanone unit. -(SUH,