Comparison of DMSO-induced denaturation
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H Iwase; M Hirai; S Arai; S Mitsuya; S Shimizu; T Otomo; M Furusaka
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Article
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1999
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Elsevier Science
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English
⚖ 117 KB
By using both wide-angle neutron and small-angle X-ray scattering techniques, we have studied the denaturation processes of hen egg-white lysozyme (HEWL) and bovine a-lactalbumin (BLA) in dimethyl sulfoxide (DMSO)/water mixtures. Although these proteins are known to be highly homologous, the present