Abstractt The cytoaolic (cEH) mad the micmsonul cpoxidc bydtolasc (mEH) hydrolyac rtytenc oxide and tram-1-pbcnylproper oxide with different enmtio~elcctivity and ~~gioxelectivity. While mEEI always leads to l rcgiospccific and enxntio4&ive opening rt the non-bcnxylic oxinnc a&on. CEH given x aon-rc
The rabbit liver microsomal biotransformation of 1,1-dialkylethylenes: Enantioface selection of epoxidation and enantioselectivity of epoxide hydrolysis
β Scribed by Giuseppe Bellucci; Cinzia Chiappe; Antonio Cordoni; Franco Marioni
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 586 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0899-0042
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Treatment of 4",S-di-G-tert-butyldimethylsilyl(or phenoxyacetyl)-7-0-trimethylsilyl-avenue&n B2a (la,b) with diethylaminosulfur trifluoride (DAST) at 20AC in dichloromethane resulted in net elimination of water to yield 65% of the 23,24-olefin (Za,b), 510% 23-fluoroavermectin derivative (3a,b), and