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Biocatalytic Potential of the Epoxide Hydrolase from Agrobacterium radiobacter AD1 and a Mutant with Enhanced Enantioselectivity

✍ Scribed by Jeffrey H. Lutje Spelberg; Rick Rink; Alain Archelas; Roland Furstoss; Dick B. Janssen

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 100 KB
Volume: 344
Category: Article
ISSN: 1615-4150
DOI: 10.1002/1615-4169(200210)344:9<980::aid-adsc980>3.0.co;2-a

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## Abstract Soluble epoxide hydrolase (EH) from the potato __Solanum tuberosum__ and an evolved EH of the bacterium __Agrobacterium radiobacter__ AD1, EchA‐I219F, were purified for the enantioconvergent hydrolysis of racemic styrene oxide into the single product (__R__)‐1‐phenyl‐1,2‐ethanediol, whi