The protective role of plasmalogens in iron-induced lipid peroxidation
โ Scribed by Pavel J. Sindelar; Zhizhong Guan; Gustav Dallner; Lars Ernster
- Book ID
- 114277069
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 116 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0891-5849
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๐ SIMILAR VOLUMES
Iron is required for the initiation of lipid peroxidation. Evidence is presented that lipid peroxidation requires both Fe 3รท and Fe aรท, perhaps with oxygen to form a Fe3+-dioxygen-Fe 2รท complex. Other mechanisms of initiation, mostly involving the iron-catalyzed formation of hydroxyl radical, axe de
## Abstract Treatment of rats with 100 mg kg^โ1^ __t__โbutyl hydroperoxide led to an enhanced ethane exhalation as a marker of __in vivo__ lipid peroxidation, as well as a moderate hepatoxicity as evidenced by a rise in plasma activities of liverโspecific enzymes (glutamateโpyruvate transaminase an