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Role of lipid peroxidation in iron-induced cellular calcium overload

✍ Scribed by Leopold J. Anghileri; Philippe Maincent; Pierre Thouvenot

Book ID
112894656
Publisher
Humana Press Inc
Year
1996
Tongue
English
Weight
381 KB
Volume
52
Category
Article
ISSN
0163-4984

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Iron is required for the initiation of lipid peroxidation. Evidence is presented that lipid peroxidation requires both Fe 3Γ· and Fe aΓ·, perhaps with oxygen to form a Fe3+-dioxygen-Fe 2Γ· complex. Other mechanisms of initiation, mostly involving the iron-catalyzed formation of hydroxyl radical, axe de