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Hepatotoxicity induced by iron overload and alcohol: Studies on the role of chelatable iron, cytochrome P450 2E1 and lipid peroxidation

✍ Scribed by Per Stål; Inger Johansson; Magnus Ingelman-Sundberg; Karin Hagen; Rolf Hultcrantz


Book ID
118567392
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
676 KB
Volume
25
Category
Article
ISSN
0168-8278

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This study investigated the role of cytochrome P-450 2E1 in enhanced microsomal lipid peroxidation in experimental alcoholic liver disease. W e also examined the contribution of this isoform to the increased microsomal injury in alcoholic liver disease caused by carbon tetrachlorideinduced or iron-i