✦ LIBER ✦

The role of iron in the initiation of lipid peroxidation

✍ Scribed by Giorgio Minotti; Steven D. Aust

Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 952 KB
Volume: 44
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(87)90050-8

No coin nor oath required. For personal study only.

✦ Synopsis

Iron is required for the initiation of lipid peroxidation. Evidence is presented that lipid peroxidation requires both Fe 3÷ and Fe a÷, perhaps with oxygen to form a Fe3+-dioxygen-Fe 2÷ complex. Other mechanisms of initiation, mostly involving the iron-catalyzed formation of hydroxyl radical, axe described and discussed from both theoretical and experimental view points.

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