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The proteasome and the degradation of oxidized proteins: Part II – protein oxidation and proteasomal degradation

✍ Scribed by Jung, Tobias; Höhn, Annika; Grune, Tilman


Book ID
122205605
Publisher
Elsevier
Year
2014
Tongue
English
Weight
681 KB
Volume
2
Category
Article
ISSN
2213-2317

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## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi