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Proteasome-dependent degradation of oxidized proteins in MRC-5 fibroblasts

โœ Scribed by Nicolle Sitte; Katrin Merker; Tilman Grune


Book ID
117110111
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
166 KB
Volume
440
Category
Article
ISSN
0014-5793

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## Abstract The generation of free radicals and the resulting oxidative modification of cell structures are omnipresent in mammalian cells. This includes the permanent oxidation of proteins leading to the disruption of the protein structure and an impaired functionality. In consequence, these oxidi