The pharmacokinetics and transdermal delivery of loteprednol etabonate and related soft steroids
โ Scribed by Thorsteinn Loftsson; Nicholas Bodor
- Book ID
- 113291856
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 439 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0169-409X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
In a recent paper in this Journal, Hochhaus et al.? discussed the pharmacokinetics and distribution of the soft glucocorticoid 1 in rats and dogs. The basis for the interest in an ester of a steroidal 20-carboxylic acid as a soft drug was that the anticipated rapid metabolism of 1 to the correspondi
The pharmacokinetic (PK) and pharmacodynamic (PD) properties of the active (S)-enantiomer of the potent dopamine (DA) agonist 5-hydroxy-2-(N,N,-di-npropylamino)tetralin (5-OH-DPAT) were investigated in a novel anesthetized animal model. First, the relationship between current density, in vivo transp