The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target
β Scribed by Hyungjin Eoh; Patrick J. Brennan; Dean C. Crick
- Book ID
- 113938044
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 351 KB
- Volume
- 89
- Category
- Article
- ISSN
- 1472-9792
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1-Deoxy-D-xyluiose 5-phosphate is biotransformed to 2-C-methyl-D-erythritol 4-phosphate in a single step in the presence of NADPH by a new recombinant enzyme named l-deoxy-D-xylulose 5-phosphate reductoisomerase purified from Escherichia coli.