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The mean residence time of drugs in the systemic circulation

✍ Scribed by Peter Veng-Pedersen; William Gillespie

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
180 KB
Volume
74
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

The relationship between drug input and
The relationship between drug input and mean residence time in the body
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The relationship between the mean residence time after oral dosing or any other non-instantaneous mode of administration (MRT,,) was explored by a series of computer simultations. MRT,, was calculated from the ratio of AUMC to A U C (where A U C and A U M C are the zeroth and first statistical momen

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## KEY WORDS Mean residence time MRT Moments Statistical moments Mean absorption time MAT Pharmacokinetics Pharmacodynamics Biopharmaceutic Mean residence time has been the subject of much research and discussion in recent pharmacokinetic literature. Unfortunately confusion can result from the def

A method for evaluating the mean residen
A method for evaluating the mean residence times of metabolites in the body, systemic circulation, and the peripheral tissue not requiring separate i.v. administration of metabolite
✍ Peter Veng-Pedersen; William R. Gillespie πŸ“‚ Article πŸ“… 1987 πŸ› John Wiley and Sons 🌐 English βš– 272 KB πŸ‘ 2 views

The evaluation of mean residence times of drugs and metabolites provides a simple measure of the tendency for such substances to remain in various parts of the body.'-7 Most attention has been given to the evaluation of the mean residence times of the parent drug'-' although it is often of interest