The interaction of metal ions with polynucleotides and related compounds: VI. Effect of metal ions on the anion-exchange behavior of the nucleotides
โ Scribed by Gunther L. Eichhorn; Wilbur W. Everett
- Book ID
- 107710642
- Publisher
- Elsevier Science
- Year
- 1965
- Tongue
- English
- Weight
- 153 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0003-2697
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๐ SIMILAR VOLUMES
## Abstract Changes in the conformation of poly(G), poly(C), poly(U), and poly(I) in the presence of divalent metal ions Mg^2+^, Ca^2+^, Mn^2+^, Co^2+^, Ni^2+^, Cu^2+^, Cd^2+^, and Zn^2+^ have been measured by means of ORD and u.v. spectra. Mg^2+^ and Ca^2+^ ions stabilize helical structures of all
Divalent metal ions have profound effects on the conformation of poly 9, as indicated by changes in optical rotatory dispersion and ultraviolet spectra, with different metal ions having distinctly different effects. At pH 6 and in the presence of 5 X 10-3&f NaCl, two moles Ni(I1) or Co(I1) per mole
The polyrihonucleotides of adenylic, cytidylic, and uridylic acids are degraded in a 2-hr. period at 64ยฐC. into low molecular weight oligoniicleot,ides and mononncleotides through the action of lanthanum ( 111) or other trivalent inner transition met,al ions. Polyinosinic arid is degraded somewhat m