## Abstract Changes in the conformation of poly(G), poly(C), poly(U), and poly(I) in the presence of divalent metal ions Mg^2+^, Ca^2+^, Mn^2+^, Co^2+^, Ni^2+^, Cu^2+^, Cd^2+^, and Zn^2+^ have been measured by means of ORD and u.v. spectra. Mg^2+^ and Ca^2+^ ions stabilize helical structures of all
Interaction of metal ions with polynucleotides and related compounds. XII. The relative effect of various metal ions on DNA helicity
โ Scribed by Eichhorn, Gunther L.; Shin, Yong Ae.
- Book ID
- 120996796
- Publisher
- American Chemical Society
- Year
- 1968
- Tongue
- English
- Weight
- 727 KB
- Volume
- 90
- Category
- Article
- ISSN
- 0002-7863
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๐ SIMILAR VOLUMES
Divalent metal ions have profound effects on the conformation of poly 9, as indicated by changes in optical rotatory dispersion and ultraviolet spectra, with different metal ions having distinctly different effects. At pH 6 and in the presence of 5 X 10-3&f NaCl, two moles Ni(I1) or Co(I1) per mole
The polyrihonucleotides of adenylic, cytidylic, and uridylic acids are degraded in a 2-hr. period at 64ยฐC. into low molecular weight oligoniicleot,ides and mononncleotides through the action of lanthanum ( 111) or other trivalent inner transition met,al ions. Polyinosinic arid is degraded somewhat m
Polyadenylic acid is degraded into niononncleotides and low molecular might, oligoniicleotides in a 20 hr. period at 64ยฐC. by the action of ;\In (II), Co (11), Xi (11), and Cri (11) ions, and in a 2 hr. period by Zn (11) ions. The latter also degrade poly C, poly U, and RNA at approsimately the same