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Interaction of metal ions with polynucleotides and related compounds. XV. Nuclear magnetic resonance studies of the binding of copper(II) to nucleotides and polynucleotides

✍ Scribed by Berger, Nathan A.; Eichhorn, Gunther L.

Book ID: 121466376
Publisher: American Chemical Society
Year: 1971
Tongue: English
Weight: 849 KB
Volume: 10
Category: Article
ISSN: 0006-2960
DOI: 10.1021/bi00786a020

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It is demonstrated that poly(A + U) and poly(1 + C) are both formed nnder low ionic strength conditions. Continuous variation studies indicate the formation of copper(I1) complexes of poly A, poly C, and poly I, but not of poly U. Copper(I1) in a I: 1 ratio to polynucleotide prevents the formation o