Interaction of metal ions with polynucleotides and related compounds. X. Studies on the reaction of silver(I) with the nucleosides and polynucleotides, and the effect of silver(I) on the zinc(II) degradation of polynucleotides

✍ Scribed by Gunther L. Eichhorn; James J. Butzow; Patricia Clark; Edward Tarien

• Publisher: Wiley (John Wiley & Sons)
• Year: 1967
• Tongue: English
• Weight: 673 KB
• Volume: 5
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.1967.360050306

✦ Synopsis

and the Rnlfiriiore City Hospitals, Baltiiizore, ~Ua~ylancl 2li?24

Synopsis

Potentiometric titration curves of the silver(1) complexes of cytidine, adenosine, and irridine show little liptake of base below pH 7, unlike the cllrve for silver(It-giianositie, which shows extensive base uptake at neut,ral pI1. This observation is correlated with spectrophotometric data showing little diffeience between the silver complex spectra of adenosine, cytidine, and uridine and the spectra of iincomplexed nucleosides, except at high pH, but showing a great difference between the silver complex spectra of guanosine and inosine and the corresponding Iincomplexed nucleosides even a t pH 6. Similar * Presented in part at the 49th Ariniial Neetirig of the Fetletyition of American Societies for ICupei~irnetitnl Biology, At la111 ic* City, N. ,J., April 1965, 21x3 * I n conformance with previous papers in this series,12 the pyrimidine rings are numh e r d in the same way as the six-membered rings of the purines.