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The induction by X-irradiation of dominant lethal mutations in spermatogonia of mice

✍ Scribed by William Sheridan


Book ID
118952072
Publisher
Elsevier Science
Year
1965
Tongue
English
Weight
434 KB
Volume
2
Category
Article
ISSN
0027-5107

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Induction of dominant lethal mutations i
✍ U. H. Ehling πŸ“‚ Article πŸ“… 1978 πŸ› Springer-Verlag 🌐 English βš– 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal