Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal
โฆ LIBER โฆ
Induction of dominant lethal mutations by alkylating agents in male mice
โ Scribed by U.H. Ehling; R.B. Cumming; H.V. Malling
- Book ID
- 118952312
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- English
- Weight
- 733 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0027-5107
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