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Induction of dominant lethal mutation in male mice by ethyl alcohol

โœ Scribed by BADR, F. M.; BADR, RAGAA S.


Book ID
109694018
Publisher
Nature Publishing Group
Year
1975
Tongue
English
Weight
268 KB
Volume
253
Category
Article
ISSN
0028-0836

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Induction of dominant lethal mutations i
โœ U. H. Ehling ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal