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Induction of dominant lethal mutations in male mice by four individual chemicals

โœ Scribed by N. Mitra; H.V. Malling


Book ID
119091603
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
66 KB
Volume
31
Category
Article
ISSN
0165-1161

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Induction of dominant lethal mutations i
โœ U. H. Ehling ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 342 KB

Using the dominant lethal assay, the ability of fosfestrol, a diethylstilboestrol derivate, to induce mutations in male mice was tested and confirmed. Up to 300 mg/kg of fosfestrol the induction of mutations occurs exclusively in spermatozoa. A dose of 600 mg/kg of fosfestrol induces dominant lethal