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The impact of CpG island methylator phenotype and microsatellite instability on tumour budding in colorectal cancer

✍ Scribed by Inti Zlobec; Michel P Bihl; Anja Foerster; Alex Rufle; Alessandro Lugli


Book ID
114729204
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
547 KB
Volume
61
Category
Article
ISSN
0309-0167

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## Abstract The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer, associated with microsatellite instability (MSI) and __BRAF__ mutation. Genome‐wide hypomethylation may also play an important role in genomic instability. How