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The effect of cellular retinoic acid binding protein-I expression on the CYP26-mediated catabolism of all-trans retinoic acid and cell proliferation in head and neck squamous cell carcinoma

✍ Scribed by Jun Yeon Won; Eui-Cheol Nam; Seung Joo Yoo; Hyun Ja Kwon; Soo Jong Um; Hye Sook Han; Sun Hee Kim; Youngro Byun; Sang Yoon Kim


Book ID
116746774
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
247 KB
Volume
53
Category
Article
ISSN
1532-8600

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## Abstract The growth of multicellular tumor spheroids, MTSs, from squamous carcinoma line MDA 886Ln was inhibited by β‐all‐trans retinoic acid (RA). Inhibition occurred within 3 to 5 days of treatment, and MTS size then remained static for up to 2 weeks. Although their growth stopped, 10‐day‐trea