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Retinoic acid 4-hydroxylase-mediated catabolism of all-trans retinoic acid and the cell proliferation in head and neck squamous cell carcinoma

✍ Scribed by Sang Yoon Kim; Seung Joo Yoo; Hyun Ja Kwon; Sun Hee Kim; Youngro Byun; Kwang-Sun Lee

Book ID
117828552
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
114 KB
Volume
51
Category
Article
ISSN
1532-8600

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## Abstract Oral squamous cell carcinoma (OSCC) may arise from potentially malignant oral lesions. All‐__trans__ retinoic acid (atRA), which plays a role in cell growth and differentiation, has been studied as a possible chemotherapeutic agent in the prevention of this progression. While the mechan