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The induction of P450-mediated oxidation of all-trans retinoic acid by retinoids in head and neck squamous cell carcinoma cell lines

✍ Scribed by Sang Yoon Kim; In Suk Han; Hwa Kyung Yu; Hye Rim Lee; Jong Woo Chung; Jee-Ho Choi; Sun Hee Kim; Youngbro Byun; Thomas E. Carey; Kwang-Sun Lee


Book ID
117180693
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
727 KB
Volume
47
Category
Article
ISSN
1532-8600

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## Abstract Oral squamous cell carcinoma (OSCC) may arise from potentially malignant oral lesions. All‐__trans__ retinoic acid (atRA), which plays a role in cell growth and differentiation, has been studied as a possible chemotherapeutic agent in the prevention of this progression. While the mechan