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Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells

✍ Scribed by Alfonso Lampen; Silke Meyer; Heinz Nau


Book ID
114147425
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
594 KB
Volume
1521
Category
Article
ISSN
0167-4781

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## Abstract We previously demonstrated that 4‐oxoretinol (4‐oxo‐ROL) activated retinoic acid receptors (RARs) in F9 stem cells. We showed that 4‐oxo‐ROL inhibited the proliferation of normal human mammary epithelial cells (HMECs). To understand the mechanisms by which 4‐oxo‐ROL regulates HMEC growt