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all-trans-Retinoic acid-induced expression and regulation of retinoic acid 4-hydroxylase (CYP26) in human promyelocytic leukemia

โœ Scribed by Bulent Ozpolat; Kapil Mehta; Ana M. Tari; Gabriel Lopez-Berestein


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
244 KB
Volume
70
Category
Article
ISSN
0361-8609

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ALL-TRANS RETINOIC ACID (ATRA) IN THE TR
โœ C. S. CHIM; Y. L. KWONG; R. LIANG; Y. C. CHU; C. H. CHAN; L. C. CHAN; K. F. WONG ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 498 KB ๐Ÿ‘ 2 views

Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,