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Pharmacokinetics of all-trans retinoic acid in adults and children with acute promyelocytic leukemia

โœ Scribed by Kimitaka Takitani; Maki Koh; Akiko Inoue; Chihiro Kawakami; Tomoko Kuno; Hiroshi Tamai

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
82 KB
Volume
81
Category
Article
ISSN
0361-8609

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All-trans retinoic acid and short-time, high-dose cytarabine in two children with acute promyelocytic leukemia
โœ Schmitt, Klaus; Zoubek, Andreas; Schwarz, Rudolf; Tulzer, Gerald; Koller, Elisab ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 347 KB ๐Ÿ‘ 1 views

We report on two girls, 3 and 13 years well tolerated, although both children were old, with acute promyelocytic leukemia critically ill. They achieved a complete remis-(APL) who were successfully treated with all-sion confirmed by light microscopy, but trans retinoic acid (ATRA) 45 mg/m\*/day. reve

ALL-TRANS RETINOIC ACID (ATRA) IN THE TR
ALL-TRANS RETINOIC ACID (ATRA) IN THE TREATMENT OF ACUTE PROMYELOCYTIC LEUKEMIA (APL)
โœ C. S. CHIM; Y. L. KWONG; R. LIANG; Y. C. CHU; C. H. CHAN; L. C. CHAN; K. F. WONG ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 498 KB ๐Ÿ‘ 2 views

Acute promyelocytic leukemia is characterized by the reciprocal translocation of chromosomes 15 and 17. All-trans retinoic acid (ATRA) efficiently induces differentiation of the abnormal promyelocytes. In this study, we had used ATRA as the primary induction therapy for 17 newly diagnosed patients,