Respective roles of hypoxia and halothan
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Hitoshi Hatano; Fumio Nomura; Kunihiko Ohnishi; Toshihiko Iijima; Akira Hayasaka
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Article
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1985
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John Wiley and Sons
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English
โ 447 KB
To evaluate the respective roles of halothane metabolism and hypoxia in rats with halothane hepatotoxicity, experiments were designed with special reference to blood gas. After pretreatment with phenobarbital (80 mg per kg., i.p.) for four consecutive days, rats were exposed to 1.0% halothane under