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Halothane Induced Hepatic Necrosis in Rats: The Role ofin VivoLipid Peroxidation

✍ Scribed by Knights, Kathleen M. ;Gourlay, Geoffrey K. ;Gibson, Robert A. ;Cousins, Michael J.

Book ID
114801103
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
629 KB
Volume
63
Category
Article
ISSN
0901-9928

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Halothane-induced hepatic microsomal lipid peroxidation in guinea pigs and rats was examined with respect to the mixed function oxidase system, anaerobic dehalogenation activity of halothane, and the antioxidant system. The levels of cytochrome P-450 and NADPH-cytochrome P-450 reductase were signifi