The clinical importance and prognostic implications of microsatellite instability in sporadic cancer
โ Scribed by D.A Lawes; S SenGupta; P.B Boulos
- Book ID
- 117818002
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 194 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0748-7983
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. Microsatellite instability (MI) has been reported in some sporadic colon tumors and in cases of hereditary nonpolyposis colorectal cancer (HNPCC). The criteria for HNPCC have not been fully defined, and clinical criteria are used to identify as many HNPCC patients as possible. To cl
## Abstract Microsatellite instability in sporadic colon cancer is associated with an improved prognosis. Recent studies, however, have suggested that microsatellite unstable cancers with mutations in the proapoptotic gene __BAX__ have a relatively poor prognosis, whereas those with mutations in tr