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Tetraploid clone characterized by two t(15;17) in five cases of acute promyelocytic leukemia

✍ Scribed by Jinlan Pan; Yongquan Xue; Huiying Qiu; Yafang Wu; Yong Wang; Jun Zhang; Juan Shen

Book ID
113513432
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
86 KB
Volume
188
Category
Article
ISSN
0165-4608

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✍ Dr. Richard S. Lemons; David Eilender; Richard A. Waldmann; Matt Rebentisch; Ann πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 881 KB

A reciprocal chromosomal translocation, t( I 5; I7)(q22;q I I .2-I2), is characteristic of acute promyelocytic leukemia (APL) of French-American-British (FAB) subtype M3, and is not associated with any other human malignancy. The non-random pattern of the APL translocations suggests that specific ge