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Hypocellular acute promyelocytic leukemia with a tetraploid clone characterized by two t(15;17)

โœ Scribed by Kensuke Kojima; Michiyoshi Imaoka; Toshiyuki Noguchi; Hiroshi Narumi; Naoyuki Uchida; Ikuya Sakai; Masaki Yasukawa; Shigeru Fujita


Book ID
114135622
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
152 KB
Volume
145
Category
Article
ISSN
0165-4608

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A reciprocal chromosomal translocation, t( I 5; I7)(q22;q I I .2-I2), is characteristic of acute promyelocytic leukemia (APL) of French-American-British (FAB) subtype M3, and is not associated with any other human malignancy. The non-random pattern of the APL translocations suggests that specific ge