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Delineation of translocation t(15; 17) in acute promyelocytic leukemia by chromosomal in situ suppression hybridization

✍ Scribed by M.R. Speicher; A. Jauch; A. Parr; R. Becher


Book ID
113239717
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
514 KB
Volume
17
Category
Article
ISSN
0145-2126

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## Abstract The genomic breakpoints in the t(15;17)(q22;q21), associated with acute promyelocytic leukemia (APL), are known to occur within three different __PML__ breakpoint cluster regions (bcr) on chromosome 15 and within __RARA__ intron 2 on chromosome 17; however, the precise mechanism by whic